Thursday, July 19, 2007

Recovering Genomic Information

If causes of genomic decay go unchecked is there any way to recover the original sequencing patterns for long dead specimens? The answer appears to be yes according to 'Molecular breeding of polymerases for amplification of ancient DNA.' A promising method exists, according to the authors of the linked abstract from Nature Biotechnology, which notes that DNA lesions accumulate unless repaired. Death stops repair but not the accumulating lesions. Accumulating lesions have implications for DNA found in connection with paleontological, archaeological and forensic endeavors.

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