Thought Leads to Physical Changes
Neuroscience: Meditation really can change the brain is a blog entry at Mindful Hack showing that rational people can interpret scientific data more than one way when scientific boundary lines are ill-defined. What is ill-defined is the relationship between thought and brain cells, or to be more specific, how changes in one lead to changes in the other. The topic has been broached many times and there is ample evidence that the way one thinks can lead to physical changes in the brain. Materialists attempt to define thought as a mere manifestation of underlying physical (biochemical) events. It is usually depicted by reference to the concept of emergence.
Emergence is a reach in my view. It is the root of the word emergency which describes how a materialist must react to evidence that a non-physical entity, like thought, changes biochemical reactions and even the brain itself. It's a case of philosophy influencing interpretations of physical data. We can measure the effects of thinking as well as the application of intelligence through the manipulation of the physical world when problems are solved or actions taken. But lets not confuse physical effects with a physical description of their cause.
You can believe thoughts are nothing but brain cells if you wish. That's a metaphysical position though. Sequencing is a major theme of this blog. Generally it is mentioned when speaking of amino acids or nucleotides. But sequencing can be thought of in terms of thoughts and brain biochemistry. Which came first, a flash of insight or some biochemical reactions associated with it? If it is ever the former then materialsim is dead.