Tuesday, June 29, 2010

Network Topologies and Biochemical Adaptation

Key Circuits Control Cell's Ability To Adapt To Changes In Its Environment is a Science Daily article. Quoting from it:

ScienceDaily (2009-08-25) -- Researchers have identified the two key circuits that control a cell's ability to adapt to changes in its environment, a finding that could have applications ranging from diabetes and autoimmune research to targeted drug development for complex diseases.

A paper on the finding was published in the August 21, 2009 edition of the journal Cell. The article is titled
Defining Network Topologies that Can Achieve Biochemical Adaptation. Biochemical adaptation is an issue around which controversy has centered during discussions of intelligent design. Michael Behe comes readily to mind.

The Science Daily article places some emphasis on adaptation to stimulus, cellular reset and homeostasis. Researchers analyzed millions of cellular circuits involved in adaptive responses. The complexity of the analysis is impressive. Interestingly a study of enzymatic regulatory networks resulted in the identification of "two core structures that are common to every adaptive response."